Physicians Worldwide

G6PD enzyme assay is used for diagnosis of G6PD deficiency. However, false-negative results (normal enzyme level) may occur in some individuals with acute hemolysis because the most severely G6PD-deficient cells have been destroyed; in such cases, testing shou…

✅Hypercalcemia: Always Interpret Calcium in Context 👉A low serum albumin can lower total calcium without reducing biologically active, ionized calcium. Conversely, critically ill patients may have unreliable albumin-corrected calcium estimates. 👉When calcium r…

🌎A fatal mistake is delaying use of epinephrine (or even not using it) in cases of mild anaphylaxis. ✅Epinephrine is the first and most important treatment for anaphylaxis, and it should be administered as soon as anaphylaxis is recognized to prevent the progr…

✅Not every patient with fever and neck stiffness has meningitis. 👉A subarachnoid hemorrhage can present with sudden severe headache ("thunderclap headache"), neck stiffness, vomiting, and even a low-grade fever due to meningeal irritation. ✅If the headache rea…

✅Infective Endocarditis: Negative Blood Cultures Do Not Exclude the Diagnosis 👉Blood cultures may be negative in infective endocarditis, particularly following prior antibiotic administration or with fastidious organisms. 👉Obtain at least three sets of blood c…

✅Reversible cerebral vasoconstriction syndrome (RCVS) 👉It is characterized by reversible narrowing and dilatation of the cerebral arteries. 👉The clinical presentation of RCVS is usually dramatic with sudden, severe thunderclap headaches that often recur over a…

✅Lifelong LDL-C lowering therapy with statins, ezetimibe, and/or bempedoic acid is indicated after any atherosclerotic cardiovascular disease (ASCVD) event(eg: MI, ischemic stroke, TIA, etc), independent of baseline LDL-C levels, to reduce cardiovascular risk.

✅The severity of acute pancreatitis is not determined by the serum amylase or lipase level. 👉The magnitude of pancreatic enzyme elevation does not reliably correlate with disease severity or predict complications. 👉Assess severity using clinical status, organ…